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It was found that naltrexone and bupropion combined, which may be marketed in the foreseeable future as Contrave, provide better weight loss results than diet and exercise alone.

Using two separate drugs to lose weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err to the side of caution and permit the FDA do its job and demand some research be done so your public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on their medications.

Researchers found that participants using this drug for a year, dropped a few pounds within a month and have kept the body weight off through the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which can make them more effective and safer.

Combo-pilling will be the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that as of right now there aren't long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure levels and heart rate, and must not be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.